Southwest Foot and Ankle Center and DFW Wound Care

How Do Amniotic Injections Work?

Amniotic injections contain abundant substances that promote healthy tissue regeneration. These components include cytokines, growth factors, fibrinogen, collagen, hyaluronic acid and messenger RNA.

This stem cell recruitment process is of particular value when a patient receives amniotic injections of PalinGen to help the body heal.

Generally speaking, amniotic injections can be described as consisting of a multipotent tissue matrix. As such, they function to fill, cover, and protect a defect or void.

What Conditions Do Amniotic Injections Help?

Essentially, amniotic injections help with wound care, controlling pain, and orthopedic uses like facilitating repair of tendons, fasciae, capsules, and ligaments. They can help chronic tendinopathies, synovial surfaces, tendonitis, and chronic fasciosis.

To break it down still further, amniotic injections can help patients deal with issues like ACL and MCL tears, biceps and triceps tendonitis, tendinosis, epicondylitis, knee scopes, rotator cuff surgery, facet osteoarthritis, foot and ankle arthroplasty, acromioclavicular joint inflammation, ACL revisions, herniated discs, AVN of the hip and other problems with the knees and hips, planar fasciitis, post-operative pain resulting from orthopedic and spinal surgery, and the need for tendon and cartilage repair.

How Do Amniotic Injections Work in Wound Care?

In wound care in particular, amniotic injections work well to fight inflammation and promote re-epithelialization, the production and migration of cells to provide temporary protection. Amniotic injections provide a new basement membrane to facilitate the latter process. Additionally, the amniotic injections inhibit TGF-beta signaling and thus, in turn, fibrosis.